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Design of the therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (TRAFFIC) trial

✍ Scribed by Robert J. Lederman; Alan N. Tenaglia; R.David Anderson; James B. Hermiller; Krishna Rocha-Singh; Farrell O. Mendelsohn; William R. Hiatt; Thomas Moon; M.J. Whitehouse; Brian H. Annex

Book ID: 113974864
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 139 KB
Volume: 88
Category: Article
ISSN: 0002-9149
DOI: 10.1016/s0002-9149(01)01622-8

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## Abstract Fibroblast growth factor 2 (FGF‐2) is a potent mitogen for mesenchymal cells, and a local application of recombinant human FGF‐2 (rhFGF‐2) in a gelatin hydrogel has been reported to accelerate bone union in our animal studies and preparatory dose‐escalation trial on patients with surgic