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Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia

✍ Scribed by Kwang-Ho Cha; Junsung Park; Wonkyung Cho; Dong-Geon Gu; Kihyang Jeong; Sung-Joo Hwang

Book ID
107642156
Publisher
Springer
Year
2009
Tongue
English
Weight
248 KB
Volume
32
Category
Article
ISSN
0253-6269

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✍ J.M. Llabot; R.H. Manzo; D.A. Allemandi πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 124 KB

Mucoadhesive tablets containing nystatin (10 mg) were evaluated in vivo. The assays were carried out with 12 healthy volunteers and the concentration of nystatin in saliva was determined at different times. Tablets remained attached to the buccal mucosa during 270 min +/- 30 min. No evidence of ulce