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Design of novel histone-derived antimicrobial peptides

✍ Scribed by Hoi See Tsao; Sara A. Spinella; Anna T. Lee; Donald E. Elmore


Book ID
116832035
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
286 KB
Volume
30
Category
Article
ISSN
0196-9781

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✍ Gang Hao; Yong-Hui Shi; Jing-Hui Han; Qi-Hui Li; Ya-Li Tang; Guo-Wei Le πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 430 KB

## Abstract We have __de novo__ designed four antimicrobial peptides AMP‐A/B/C/D, the 51‐residues peptides, which are based on the conserved sequence of cecropin. In the present study, the four peptides were chemically synthesized and their activities assayed. Their secondary structure, amphipathic