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Design of inhibitors for the transporter associated with antigen processing (TAP) using peptidomimetics

✍ Scribed by M. Grommé; R. van der Valk; K. Sliedregt; L. Vernie; R. Liskamp; G. Hämmerling; J.-O. Koopmann; F. Momburg; J. Neefjes

Book ID
108408999
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
161 KB
Volume
56
Category
Article
ISSN
0165-2478

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📜 SIMILAR VOLUMES

The rational design of TAP inhibitors us
The rational design of TAP inhibitors using peptide substrate modifications and peptidomimetics
✍ Monique Grommé; Richard van der Valk; Karen Sliedregt; Leen Vernie; Rob Liskamp; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 746 KB

## Abstract The major histocompatibility complex (MHC)‐encoded transporter associated with antigen processing (TAP) translocates peptides from the cytosol into the lumen of the endoplasmic reticulum. This step precedes the binding of peptides to MHC class I molecules and is essential for cell surfa