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Design of experiments for the determination of the detection limit in chemical analysis

✍ Scribed by Ilya Kuselman; Avinoam Shenhar

Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
370 KB
Volume
306
Category
Article
ISSN
0003-2670

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✦ Synopsis

The uncertainty of values of the detection limit in chemical analysis is described considering the reasonable risk of false analyte detection and false nondetection, the number of analytical results and some other parameters of the experimental design. Calculations have been made of minimum number of certified reference materials or standard solutions and number of replicates needed to design the experiments for determination of detection limit based on calibration data.

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