Design of Axially Chiral Dicarboxylic Acid for Asymmetric Mannich Reaction of Arylaldehyde N -Boc Imines and Diazo Compounds
β Scribed by Hashimoto, Takuya; Maruoka, Keiji
- Book ID
- 124148539
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 50 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0002-7863
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## Abstract **The moderate nucleophilicity** of the axially chiral amino sulfonamide (__S__)β**1** suppresses the problematic side reactions, including aldol reactions, in the asymmetric Mannich reaction of NβBocβprotected imines with aldehydes. The corresponding adducts are obtained in good yield
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