Detection of C1236T, G2677T/A, and C3435
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Bing Chen; Jie Fang; Weixia Zhang; Zhao Jin; Zichen Yu; Weimin Cai
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Article
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2009
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John Wiley and Sons
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English
β 217 KB
C1236T, G2677T/A, and C3435T polymorphism of the multidrug resistance (MDR1) gene have substantial impact on expression or activity of P-glycoprotein (Pgp). We developed new methods based on amplification refractory mutation system (ARMS) to detect these polymorphisms. Tetra-primers amplification in