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Design of a 4-helix bundle protein: synthesis of peptides which self-associate into a helical protein

โœ Scribed by Ho, Siew Peng; DeGrado, William F.


Book ID
120297094
Publisher
American Chemical Society
Year
1987
Tongue
English
Weight
967 KB
Volume
109
Category
Article
ISSN
0002-7863

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Norbornene-supported bis-helical peptides with the general structure NBE(Aib n ) 2 (NBE: 2,3-trans-norbornene dicarbonyl unit; Aib: โฃ,โฃะˆ-dimethyl glycine unit; n ฯญ 4,5) have been synthesized and examined for self-assembly preferences in the solid state. An x-ray study has revealed a phenomenon of Ja