Design and uses of selective agonistic and antagonistic analogs of the neuropeptides oxytocin and vasopressin
β Scribed by Maurice Manning; Wilber H. Sawyer
- Book ID
- 119507143
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 514 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0166-2236
No coin nor oath required. For personal study only.
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## Abstract This tribute to Bruce Merrifield traces the author's fortuitous path in 1964 from Vincent du Vigneaud's laboratory to the laboratory of D. W. Woolley to learn the solid phase method and then to his first faculty position in the Department of Biochemistry, McGill University, Montreal in
We report here the solid-phase synthesis and vasodepressor potencies of a new lead vasopressin (VP) hypotensive peptide [1(beta-mercapto-beta,beta-pentamethylenepropionic acid)-2-0-ethyl-D-tyrosine, 3-arginine, 4-valine, 7-lysine, 9-ethylenediamine] lysine vasopressin, d(CH(2))(5)[D-Tyr(Et)(2), Arg(