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Design and Synthesis of Two New Peptide Substrates for the Specific and Sensitive Monitoring of Casein Kinases 1 and 2

โœ Scribed by O. Marin; F. Meggio; L.A. Pinna


Book ID
115574163
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
389 KB
Volume
198
Category
Article
ISSN
0006-291X

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A fluorescent water-soluble substrate for phosphatidylinositol-specific phospholipase C was synthesized. The diacylglycerol moiety of the natural substrate, phosphatidylinositol, was replaced by the fluorescent moiety, 2-naphthol, resulting in the synthetic substrate, racemic 2-naphthyl myo-inositol