Design and synthesis of substrate analogs for the inhibition of dehydroquinate synthase
β Scribed by Nicholas Nikolaides; Bruce Ganem
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 194 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Benzphetamine, an amphetamine with sympathomimetic stimulant activity in the central nervous system, is a substrate for cytochromes P450 with highest metabolic turnover being catalyzed by cytochrome P4502B1. We synthesized three photolabile azido-compound analogs, \(\quad N\)-( \(p\)-azidobenzyl)- \
## Abstract __Dolichols are polyisoprenoid lipid components of mammalian membranes consisting of an average of 20 headβtoβtail linked isoprene units of which the first isoprene is fully saturated. The unusual size of these lipids is intriguing and poses questions about the role of dolichol structur