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Design and synthesis of some new pyranoxanthenones with cytotoxic activity

✍ Scribed by Konstantinos Ghirtis; Nicole Pouli; Panagiotis Marakos; Alexios-Leandros Skaltsounis; Stephane Leonce; Ghanem Atassi; Daniel H. Caignard

Publisher
Journal of Heterocyclic Chemistry
Year
2001
Tongue
English
Weight
79 KB
Volume
38
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

As part of a research program directed towards the design and synthesis of pyranoxanthones structurally related to acronycine, we present here the synthesis and cytotoxic activity of the pyranoxanthones 3 and 4 (X= H, Br; R= H, OMe; R'= H, Ac). Some of these compounds inhibit L1210 cell proliferation.

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