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Design and synthesis of positional isomers of 1-alkyl-2-trifluoromethyl-5 or 6-substituted benzimidazoles and their antimicrobial activity

✍ Scribed by G. Sathaiah, A. Ravi Kumar, A. Chandra Shekhar, K. Raju, P. Shanthan Rao, B. Narsaiah, A. Raghuram Reddy, D. Lakshmi, B. Sridhar


Book ID
118778193
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
424 KB
Volume
22
Category
Article
ISSN
1054-2523

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Synthesis of 1,2,5(6)-Trisubstituted Ben
✍ Hakan GΓΆker; Canan Kus; Ufuk Abbasoglu πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 571 KB

A series of 22 benzimidazoles, having several substituents on the azole and benzene nuclei, were prepared and evaluated in vitro for antimicrobial activity. At first 2-chloro or 2-chloromethyl-5(6>sbsti~ed-lH-benzimidazoles were synthesized, which were then substituted at C-2 with several piperazine