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Design and Synthesis of Novel α 1a Adrenoceptor-Selective Dihydropyridine Antagonists for the Treatment of Benign Prostatic Hyperplasia

✍ Scribed by Nagarathnam, Dhanapalan; Wetzel, John M.; Miao, Shou Wu; Marzabadi, Mohammad R.; Chiu, George; Wong, Wai C.; Hong, Xingfang; Fang, James; Forray, Carlos; Branchek, Theresa A.; Heydorn, William E.; Chang, Raymond S. L.; Broten, Theodore; Schorn, Terry W.; Gluchowski, Charles


Book ID
121426995
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
364 KB
Volume
41
Category
Article
ISSN
0022-2623

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## Aims: To investigate urodynamically the effects of silodosin, a new alpha(1a)-adrenoceptor-selective antagonist, in the treatment of benign prostatic hyperplasia (bph). ## Methods: Thirty six male patients with bph (69.9 +/- 7.3 years), who were referred as candidates for surgery, were treated