As a part of our continuing study of colchicinoids as therapeutically useful antitumor drugs, thiocolchicine derivatives, including their phosphate and other water soluble salts, were synthesized and evaluated for inhibition of tubulin polymerization and for in vitro cytotoxicity. Three compounds, 7
β¦ LIBER β¦
Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents
β Scribed by Wang, Xiao-Feng; Tian, Xing-Tao; Ohkoshi, Emika; Qin, Bingjie; Liu, Yi-Nan; Wu, Pei-Chi; Hour, Mann-Jen; Hung, Hsin-Yi; Qian, Keduo; Huang, Rong; Bastow, Kenneth F.; Janzen, William P.; Jin, Jian; Morris-Natschke, Susan L.; Lee, Kuo-Hsiung; Xie, Lan
- Book ID
- 121650083
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 584 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0960-894X
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## Abstract For Abstract see ChemInform Abstract in Full Text.