Design and Synthesis of an Fmoc-SPPS-Compatible Amino Acid Building Block Mimicking the Transition State of Phosphohistidine Phosphatase

Design and synthesis of novel nonpolar h

Design and synthesis of novel nonpolar host peptides for the determination of the 310- and α-helix compatibilities of α-amino acid buildig blocks: An assessment of α,α-disubstituted glycines

✍ Daniel Obrecht; Michael Altorfer; Udo Bohdal; John Daly; Walter Huber; Alexander 📂 Article 📅 1997 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 923 KB

The present work describes three novel nonpolar host peptide sequences that provide a ready assessment of the 3 10 -and a-helix compatibilities of natural and unnatural amino acids at different positions of small-to medium-size peptides. The unpolar peptides containing Ala, Aib, and a C-terminal p-i