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Design and synthesis of AB3-type (A = 1,3,5-benzenetricarbonyl unit; B = Glu diOME or Glu7 octa OMe) peptide dendrimers: Crystal structure of the first generation

✍ Scribed by Darshan Ranganathan; Sunita Kurur; Richard Gilardi; Isabella L. Karle


Publisher
Wiley (John Wiley & Sons)
Year
2000
Tongue
English
Weight
227 KB
Volume
54
Category
Article
ISSN
0006-3525

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✦ Synopsis


The first generation molecule of glutamic acid-based dendrons on a 1,3,5-benzenetricarbonyl core leads to a cylindrical assembly as demonstrated by single crystal x-ray diffraction. The benzenestack (A) is stabilized by vertical NH . . . OAC hydrogen bonding with each subunit participating in three intermolecular hydrogen bonds related by three-fold rotation symmetry.