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Design and Synthesis of A3 Adenosine Receptor Ligands, 3′-Fluoro Analogues of Cl-IB-MECA

✍ Scribed by Hea Ok Kim; Moo Hong Lim; Jae Gyu Park; Hyung Ryong Moon; Kenneth A. Jacobson; Hee-Doo Kim; Moon Woo Chun; Lak Shin Jeong

Publisher
John Wiley and Sons
Year
2004
Weight
55 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract Modification of the ribose moiety of nucleotides and nucleosides has provided new insights into structural and conformational requirements for ligands at P2Y nucleotide receptors and at adenosine receptors (ARs). Methanocarba derivatives (containing a rigid bicyclic ring system in place