𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Design and Synthesis of a PSMA Inhibitor–Doxorubicin Conjugate for Targeted Prostate Cancer Therapy

✍ Scribed by Sarva Jayaprakash; Xinning Wang; Warren D. Heston; Alan P. Kozikowski


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
208 KB
Volume
1
Category
Article
ISSN
1860-7179

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis of a Novel Pentagastrin-Drug C
✍ Lutz F. Tietze; Olaf Panknin; Felix Major; Birgit Krewer 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 335 KB 👁 1 views

## Abstract The synthesis of the novel pentagastrin seco‐CBI conjugate **3**, which is based on the highly cytotoxic antitumor antibiotic (+)‐duocarmycin SA (**1**), is reported. A key step in the synthesis is the palladium‐catalyzed carbonylation of aryl bromide **7** to give the benzyl ester **16

Mass spectral analyses of labile DOTA-NH
✍ Sharon X. Lu; Edward J. Takach; Marjorie Solomon; Qing Zhu; Say-Jong Law; Frank 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 232 KB

Prostate specific membrane antigen (PSMA) is a well-characterized glycoprotein overexpressed on the surface of prostate cancer cells. The novel radiopharmaceutical 1,4,7,10-tetraazacyclododecane-N,N 0 ,N 00 ,N 000 -tetraacetic acid (DOTA) radiolabeled with Yttrium ( 90 Y) or Indium ( 111 In) conjuga

A hybrid protein comprising ATF domain o
✍ Qiming Sun; Qian Xu; Xiangbai Dong; Lin Cao; Xiaofeng Huang; Qingang Hu; Zi-Chun 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 693 KB

## Abstract Directional and controllable degradation of extracellular matrix mediated by the uPA‐uPA receptor (uPAR) system is ubiquitously implicated in tumor establishment, invasion and metastasis. Targeting the excessive activation of this system as well as the proliferation of the tumor vascula