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Design and synthesis of a cis-gly-pro, type-VI turn, dipeptide mimetic and its use in fmoc-solid phase peptide synthesis

✍ Scribed by Dieter Gramberg; John A. Robinson


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
387 KB
Volume
35
Category
Article
ISSN
0040-4039

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✦ Synopsis


The Fmoc-protected bicyclic mobxuks 7 and 8 have been produced as cti-Gly-Ro peptide mimetics in nine synthetic steps st&n8 from q&ally pure (It)-2-allylproline. The& ose in solid-phase peptick synthesis has been dunon@ated by their incorpowtion into analo8w of ci.&ly%?-brrdykinin.