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Design and synthesis of 2-phenylimidazo[1,2-a]pyridines as a novel class of melatonin receptor ligands

✍ Scribed by Saïd El Kazzouli; Amaury Griffon du Bellay; Sabine Berteina-Raboin; Philippe Delagrange; Daniel-Henry Caignard; Gérald Guillaumet


Book ID
113583033
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
350 KB
Volume
46
Category
Article
ISSN
0223-5234

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Synthesis of 4-aza analog of ramelteon:
✍ Tatsuki Koike; Yasutaka Hoashi; Takafumi Takai; Osamu Uchikawa 📂 Article 📅 2011 🏛 Elsevier Science 🌐 French ⚖ 408 KB

Intramolecular Diels-Alder reaction Desilylation-cyclization a b s t r a c t The 4-aza analog of ramelteon (À)-1, a novel tricyclic 1,6,7,8-tetrahydro-2H-cyclopenta[d]furo[2,3-b]pyridine derivative, was synthesized via the intramolecular inverse electron demand Diels-Alder reaction followed by fluor