## Abstract The sensitivity that can be obtained with the quadrupole ion trap for onβline CE analysis using a sheathless electrospray interface and goldβtipped columns is examined. Capillaries of different i.d. are compared in continuous infusion experiments and the effects of sheath solvents on th
Design and Performance of a Universal Sheathless Capillary Electrophoresis to Mass Spectrometry Interface Using a Split-Flow Technique
β Scribed by Moini, Mehdi
- Book ID
- 120467220
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 64 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0003-2700
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A novel microelectrospray interface for the on-line coupling of capillary-zone electrophoresis (CZE) and mass spectrometry is described. The outlet of the fused-silica CZE capillary is tapered and serves as the microspray tip. The spray does not contain a sheath flow nor does the capillary tip conta
When optimizing a capillary electrophoresis/electrospray ionization mass spectrometry (CE/ESI-MS) system, consideration has to be given not only to the separation but also to the electrospray stability. Methods developed for CE/UV analysis of drugs and peptides were considered and modified to be sui