Design and operation of an automated high-throughput monoclonal antibody facility
β Scribed by Daniel Layton, Caroline Laverty, Edouard C. Nice
- Book ID
- 120908379
- Publisher
- Springer-Verlag
- Year
- 2012
- Tongue
- English
- Weight
- 509 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1867-2450
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The purpose of this study was to demonstrate the utility of combining a design of experiment (DOE) approach with high-throughput formulation screening to identify the main factors affecting protein thermostability and solution viscosity. The optimization of buffer compositions was guided by statisti