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Design and interpretation of rat liver UDS assays

✍ Scribed by Kennelly, J. C.


Book ID
115454291
Publisher
Oxford University Press
Year
1995
Tongue
English
Weight
630 KB
Volume
10
Category
Article
ISSN
0267-8357

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Allylisothiocyanate (AITC) has been evaluated for its ability to initiate unscheduled DNA synthesis (UDS) in the livers of male rats in vivo. Specific Pathogen Free outbred albino Hsd/Ola Sprague-Dawley rats were exposed by oral gavage to 37.5 or 125 mg/kg AITC in corn oil and hepatocytes assessed f