The aim of this study was the preparation and in vivo evaluation of a nasal insulin delivery system based on thiolated chitosan. 2-Iminothiolane was covalently attached to chitosan. The resulting conjugate (chitosan-TBA) exhibited 304.9 +/- 63.5 micromol thiol groups per gram polymer. Microparticles
Design and in vivo evaluation of a patch system based on thiolated polymers
✍ Scribed by Herbert Hoyer; Melanie Greindl; Andreas Bernkop-Schnürch
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 157 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0022-3549
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