Design and Biological Activity of ( S )-4-(5-{[1-(3-Chlorobenzyl)-2- oxopyrrolidin-3-ylamino]methyl}imidazol-1-ylmethyl)benzonitrile, a 3-Aminopyrrolidinone Farnesyltransferase Inhibitor with Excellent Cell Potency

✍ Scribed by Bell, Ian M.; Gallicchio, Steven N.; Abrams, Marc; Beshore, Douglas C.; Buser, Carolyn A.; Culberson, J. Christopher; Davide, Joseph; Ellis-Hutchings, Michelle; Fernandes, Christine; Gibbs, Jackson B.; Graham, Samuel L.; Hartman, George D.; Heimbrook, David C.; Homnick, Carl F.; Huff, Joel R.; Kassahun, Kelem; Koblan, Kenneth S.; Kohl, Nancy E.; Lobell, Robert B.; Lynch, Joseph J.; Miller, Patricia A.; Omer, Charles A.; Rodrigues, A. David; Walsh, Eileen S.; Williams, Theresa M.

• Book ID: 120031335
• Publisher: American Chemical Society
• Year: 2001
• Tongue: English
• Weight: 316 KB
• Volume: 44
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm010156p