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Design and biological activity of imidazole-containing peptidomimetics with a broad-spectrum antioxidant activity

✍ Scribed by Mark A. Babizhayev; Yann Courbebaisse; Jean-François Nicolay; Yuri A. Semiletov

Book ID
105576414
Publisher
Springer Netherlands
Year
1998
Tongue
English
Weight
1001 KB
Volume
5
Category
Article
ISSN
1573-3149

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✍ Dr. Varsha V. Kapoerchan; Dr. Annemiek D. Knijnenburg; Miquel Niamat; Emile Spal 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 437 KB

## Abstract The cyclic cationic antimicrobial peptide gramicidin S (GS) is an effective topical antibacterial agent that is toxic for human red blood cells (hemolysis). Herein, we present a series of amphiphilic derivatives of GS with either two or four positive charges and characteristics ranging