## Abstract An appealing genomeβwide association study design compares one large control group against several disease samples. A pioneering study by the Wellcome Trust Case Control Consortium that employed such a design has identified multiple susceptibility regions, many of which have been indepe
β¦ LIBER β¦
Design and analysis of multiple diseases genome-wide association studies without controls
β Scribed by Zhongxue Chen; Hanwen Huang; Hon Keung Tony Ng
- Book ID
- 119241342
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 852 KB
- Volume
- 510
- Category
- Article
- ISSN
- 0378-1119
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## Abstract Genomeβwide association studies have recently identified many new loci associated with human complex diseases. These newly discovered variants typically have weak effects requiring studies with large numbers of individuals to achieve the statistical power necessary to identify them. Lik