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Design and Analysis of Drug Combination Experiments

✍ Scribed by Roel Straetemans; Timothy O'Brien; Luc Wouters; Jacky Van Dun; Michel Janicot; Luc Bijnens; Tomasz Burzykowski; Marc Aerts

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
238 KB
Volume
47
Category
Article
ISSN
0323-3847

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A rational approach is needed to maximize the chances of finding new drugs, and to exploit the opportunities of potential new drug targets emerging from genomic and proteomic initiatives, and from the large libraries of small compounds now readily available through combinatorial chemistry. Despite a