This book discusses the analysis of gene expression profile data from DNA micorarray studies and the design of such studies. The book will address design and analysis issues for both of the major classes of DNA microarrays, the cDNA microarrays and the oligonucleotide arrays. DNA microarrays are a n
Design and Analysis of DNA Microarray Investigations
โ Scribed by Yogesh Jaluria
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Leaves
- 204
- Series
- Dekker Mechanical Engineering
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
โฆ Synopsis
This book discusses the analysis of gene expression profile data from DNA micorarray studies and the design of such studies. The book will address design and analysis issues for both of the major classes of DNA microarrays, the cDNA microarrays and the oligonucleotide arrays. DNA microarrays are a new technology that is revolutionizing biological and biomedical research. Most biologists are trying to analyze their own data using a variety of commercial and public domain software. This book will provide an authoritative review of the methods available and present it in a manner that is intelligible to biologists.
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<p><P>This book is targeted to biologists with limited statistical background and to statisticians and computer scientists interested in being effective collaborators on multi-disciplinary DNA microarray projects. State-of-the-art analysis methods are presented with minimal mathematical notation and
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Considered highly exotic tools as recently as the late 1990s, microarrays are now ubiquitous in biological research. Traditional statistical approaches to design and analysis were not developed to handle the high-dimensional, small sample problems posed by microarrays. In just a few short years the