𝔖 Bobbio Scriptorium
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Design and Analysis of Clinical Trials with Time-to-Event Endpoints edited by Karl E. Peace

✍ Scribed by Val Gebski


Book ID
110971750
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
66 KB
Volume
53
Category
Article
ISSN
1369-1473

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Exploration of the variation of treatment effect over time in randomized clinical trials with low event rates is limited by lack of power. A meta-analysis on individual patient data from such trials can partly solve the problem, but brings other computational difficulties. Using an example in hypert