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Desensitization of renal D1 dopamine receptors by G protein-coupled receptor kinases and endocytosis

✍ Scribed by Hironobu Watanabe; Jing Xu; Chikh Bengra; Pedro A Jose; Robin A Felder

Book ID
117600527
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
50 KB
Volume
14
Category
Article
ISSN
0895-7061

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Desensitization of human renal D1 dopami
Desensitization of human renal D1 dopamine receptors by G protein-coupled receptor kinase 4
✍ Watanabe, Hidetsuna; Xu, Jing; Bengra, Chikh; Jose, Pedro A.; Felder, Robin A. πŸ“‚ Article πŸ“… 2002 πŸ› Nature Publishing Group 🌐 English βš– 612 KB

## Background: The d1 dopamine receptor, expressed in several nephron segments, participates in the regulation of water and electrolyte transport. because the renal d1 receptor is desensitized in genetic hypertension, we sought to determine the mechanism(s) of the desensitization of d1 receptors en