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Desensitization of 5-HT1A Autoreceptors by a Low Chronic Fluoxetine Dose Effect of the Concurrent Administration of WAY-100635

✍ Scribed by Ildefonso Hervás; M.Teresa Vilaró; Luz Romero; M.Cecilia Scorza; Guadalupe Mengod; Francesc Artigas

Book ID
114280707
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
438 KB
Volume
24
Category
Article
ISSN
1470-634X

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The present study investigated alterations of the regulation of serotonin (5-hydroxytryptamine; 5-HT) release by 5-HT 1A autoreceptors following single and repeated treatment with the 5-HT 1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). Rats were pretreated with 8-OH-DPAT (1.