Description of Japanese twins with cleft lip, cleft palate, or both
β Scribed by Nagato Natsume; Fumihiko Sato; Kouji Hara; Tsuyoshi Kawai; Nobumi Ogi
- Book ID
- 117724903
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 566 KB
- Volume
- 89
- Category
- Article
- ISSN
- 1528-395X
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## Abstract Nonsyndromic cleft lip and palate (CLP) is among the most common human birth defects. Transmission patterns suggest that the causes are βmultifactorialβ combinations of genetic and nongenetic factors, mostly distinct from those causing cleft secondary palate (CP). The major etiological
Twin studies have played an important role in attempts to unravel the genetic contribution to diseases with adult onset, but have not been extensively utilized in efforts to establish the genetic contribution to common congenital anomalies. The paucity of twin research on congenital anomalies is par