## Abstract Syntheses of the [Lys^7^]‐ and [Hyp^6^,Lys^7^]‐dermorphin analogues in which either Tyr^5^ or Hyp^6^ are __O__‐glucosylated are described. For comparison, the carbohydrate‐free peptides have also been prepared. Structural investigations by FT‐IR and CD measurements were carried out on t
✦ LIBER ✦
Dermorphin and Deltorphin Glycosylated Analogues: Synthesis and Antinociceptive Activity after Systemic Administration †
✍ Scribed by Negri, Lucia; Lattanzi, Roberta; Tabacco, Fabio; Orrù, Luigi; Severini, Cinzia; Scolaro, Barbara; Rocchi, Raniero
- Book ID
- 126831123
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 47 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0022-2623
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## Abstract Syntheses are described of new dermorphin and [D‐Ala^2^]deltorphin I analogues in which the phenylalanine, the tyrosine or the valine residues have been substituted by the corresponding __N__‐alkyl‐glycine residues. Structural investigations by CD measurements in different solvents and