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Dermatomyositis and transitional cell carcinoma of the bladder: a rare paraneoplastic syndrome associated with tumor recurrence

✍ Scribed by Carmen García-Donoso; Alfonso Sánchez-Muñoz; Francisco López-Medrano

Book ID
117644395
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
137 KB
Volume
14
Category
Article
ISSN
0953-6205

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## Abstract Epigenetic silencing of tumor suppressor genes by promoter hypermethylation has been shown for a variety of genes in bladder cancer. Various p53 target genes have been investigated, but only few demonstrated promoter hypermethylation when semiquantitative detection methods were applied.