Dermatoglyphics in 45X/46XX gonadal dysgenesis
β Scribed by Sandra R. Wolman; Allan A. Horland; Ralph David
- Book ID
- 119838477
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 137 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0009-9163
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Pure gonadal dysgenesis with 46,XX genotype is a rare abnormality with unknown etiology. Although sensorineural deafness has been described with 46,XX gonadal dysgenesis, the majority of reported cases of 46,XX gonadal dysgenesis have no associated physical abnormalities. We report a patient with 46
A search for Y-specific DNA sequences has been performed in a sample of seven 46,XX true hermaphrodites and one 45,X mixed gonadal dysgenesis case and compared with a sample of 11 XX males. Using six Y-specific DNA probes no hybridization signal was obtained in the hermaphrodite group; in contrast,