Dermatoglyphic and cytogenetic studies in parents of children with trisomy 21
β Scribed by Rina Schmidt; Hanna Dar; Harold M. Nitowsky
- Book ID
- 119839241
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 431 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0009-9163
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A study of karyotypes and neutrophil alkaline phosphatase (NAP) was carried out for 66 parents (33 couples) of trisomy 21 children and for 60 control parents (30 couples). Enzyme activity was determined simultaneously by biochemical and cytochemical techniques. In the mothers of trisomy 21 children
The authors investigated the age of the parents and grandmothers of 262 children with simple trisomy 21. In cases in which the mother was under 30, the mean grandmaternal age was higher than that of the controls. This might mean that some of these cases, being the children of old mothers, began thei