Dermal-epidermal interactions and the site of action of the yellow (Ay) and nonagouti (a) coat color genes in the mouse
โ Scribed by Timothy W. Poole
- Book ID
- 118872838
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 426 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0012-1606
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Very few melanocytes can be detected by the DOPA reaction in the dorsal epidermis of newborn lethal yellow mice (Ay/a). Nevertheless, the epidermis contains a considerable number of melanoblasts (cells positive for the combined DOPA-premelanin reaction). On the other hand, numerous melanocytes as we
The tails of agouti C3H/HeJmsHir mice are completely pigmented, whereas the tails of black C57BL/10JHir animals possess unpigmented tips. Genetic analysis indicates that white tail-tipping is due to an autosomal recessive gene, with incomplete penetrance, that segregates independently from the gene