Deriving and identifying hepatocytes from embryonic stem cells
β Scribed by Alistair J. Watt; Lesley M. Forrester
- Book ID
- 107567949
- Publisher
- Humana Press Inc
- Year
- 2006
- Tongue
- English
- Weight
- 145 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1550-8943
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We investigated the role of the hematopoietically expressed homeobox (Hex) in the differentiation and development of hepatocytes within embryonic stem cell (ESC)-derived embryoid bodies (EBs). Analyses of hepatic endoderm derived from Hex(-/-) EBs revealed a dramatic reduction in the levels of album
## Abstract Embryonic stem cells (ESCs) can differentiate into all somatic cell types, thereby providing a robust cell source for regenerative medicine therapies. ESCs are commonly induced to differentiate via threeβdimensional cell aggregates called embryoid bodies (EBs), which recapitulate cellul