A concise formulation is presented for the derivatives of Green's functions of three-dimensional generally anisotropic elastic materials. Direct calculation for derivatives of the Green's function on the Cartesian coordinate system is a common practice, which, however, usually leads to a complicated course. In this paper the Green's function derived by Ting and Lee [Ting, T.C.T., Lee, V.G., 1997. The three-dimensional elastostatic Green's function for general anisotropic linear elastic solids. The Quarterly Journal of Mechanics and Applied Mathematics 50 (3) 407-426] is extended to obtain the derivatives. Using a spherical coordinate system, the Green's function can be shown as the composition of two independent functions, one depends only on the radial distance of the field point to the origin and the other is in spherical angles. The method of derivation is based on the total differential scheme and then takes its partial differentiation accordingly. With the application of Cauchy residue theorem, the contour integral can be evaluated in terms of the Stroh eigenvalues of a sextic equation. For the degenerate case, evaluation of residues at multiple poles is also given. Applications of the present result are made to examine the Green's functions and stress components for isotropic and transversely isotropic materials. The results are in exact agreement with existing solutions.