𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer

✍ Scribed by Angel Alkarain, Joyce Slingerland

Book ID
120701215
Publisher
BioMed Central
Year
2003
Tongue
English
Weight
99 KB
Volume
6
Category
Article
ISSN
1465-5411

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Regulation of the Cdk inhibitor p27 and
Regulation of the Cdk inhibitor p27 and its deregulation in cancer
✍ J. Slingerland; M. Pagano πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 137 KB πŸ‘ 1 views

p27 is a cell cycle inhibitor whose cellular abundance increases in response to many antimitogenic stimuli. In this review, we summarize the current knowledge on p27 function and its regulation by synthesis and by ubiquitin-mediated degradation. Importantly, p27 degradation is enhanced in many aggre