Here we examine the effect of adding carvedilol (CVD) to University of Wisconsin (UW) solution on the preservation of steatotic and nonsteatotic livers during cold ischemia and after normothermic reperfusion. We used an isolated perfused rat liver model. The following protocols were evaluated. Proto
β¦ LIBER β¦
Deregulation of iron homeostasis and cold-preservation injury to rat liver stored in University of Wisconsin solution
β Scribed by Samuel Wyllie; Philip Seu; Feng Q. Gao; John A. Goss
- Book ID
- 111723343
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 271 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1527-6465
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Preservation of the liver involves a period of cold (0" to 4" C) ischemia; the longer the ischemic period, the greater the injury to the liver. The mechanisms for cold-induced ischemic injury are not known, but it is clear that after preservation the liver has a reduced capacity to regenerate high-e