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Deregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive childhood T-cell acute lymphoblastic leukemia

✍ Scribed by Kristina Karrman; Anna Andersson; Helga Björgvinsdóttir; Bodil Strömbeck; Carin Lassen; Tor Olofsson; Florence Nguyen-Khac; Roland Berger; Olivier Bernard; Thoas Fioretos; Bertil Johansson

Book ID: 114676152
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 257 KB
Volume: 77
Category: Article
ISSN: 0902-4441
DOI: 10.1111/j.0902-4441.2006.t01-1-ejh2553.x

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Activation of HOX11L2 by juxtaposition with 3′-BCL11B in an acute lymphoblastic leukemia cell line (HPB-ALL) with t(5;14)(q35;q32.2)

✍ Roderick A.F. MacLeod; Stefan Nagel; Maren Kaufmann; Johannes W.G. Janssen; Hans 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 360 KB

Cytogenetic analysis of a pediatric T-cell acute lymphoblastic leukemia (ALL) cell line (HPB-ALL) revealed the cryptic t(5;14)(q35;q32.2), recently found in 15-20% pediatric T-ALL patients, with 5q35 and 14q32.2 breakpoints at 5'-HOX11L2 and 3'-BCL11B, respectively. Expression of both BCL11B, which