## Abstract Aurora/Ipl1‐related kinases are a conserved family of proteins that are essential for the regulation of chromosome segregation and cytokinesis during mitosis. Aberrant expression and activity of these kinases occur in a wide range of human tumours and have been implicated in mechanisms
✦ LIBER ✦
Deregulation of Aurora kinase gene expression in human testicular germ cell tumours
✍ Scribed by E. Baldini; Y. Arlot-Bonnemains; M. Mottolese; S. Sentinelli; B. Antoniani; S. Sorrenti; M. Salducci; E. Comini; S. Ulisse; M. D’Armiento
- Book ID
- 108893380
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 303 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0303-4569
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## Abstract To identify key molecules that regulate germ cell proliferation and differentiation, we have attempted to isolate protein kinase genes preferentially expressed in germ line cells. One such cDNA cloned from murine embryonic germ(EG) cells encodes a nonreceptor type serine/threonine kinas