𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Deregulated degradation of the cdk inhibitor p27 and malignant transformation

✍ Scribed by Joanna Bloom; Michele Pagano

Book ID
114340585
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
354 KB
Volume
13
Category
Article
ISSN
1044-579X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Regulation of the Cdk inhibitor p27 and
Regulation of the Cdk inhibitor p27 and its deregulation in cancer
✍ J. Slingerland; M. Pagano πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 137 KB πŸ‘ 1 views

p27 is a cell cycle inhibitor whose cellular abundance increases in response to many antimitogenic stimuli. In this review, we summarize the current knowledge on p27 function and its regulation by synthesis and by ubiquitin-mediated degradation. Importantly, p27 degradation is enhanced in many aggre

Apoptosis of malignant cells in Hodgkin'
Apoptosis of malignant cells in Hodgkin's disease is related to expression of the cdk inhibitor p27KIP1
✍ Kolar, Zdenek; Flavell, Joanne R.; Ehrmann, Jiri; Rihakova, Petra; Macak, Jirka; πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 268 KB πŸ‘ 2 views

Previous results from B-cell chronic lymphocytic leukaemia suggest that expression of p27KIP1 might be important in protection from apoptosis. Given the relevance of apoptosis to the pathogenesis of Hodgkin's disease (HD), it was decided to examine the expression of p27KIP1 in relation to apoptosis