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Deregulated c-myc expression in quiescent CHO cells induces target gene transcription and subsequent apoptotic phenotype

โœ Scribed by FANG, Chang Ming; SHI, Can; XU, Yong Hua


Book ID
110020395
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
341 KB
Volume
9
Category
Article
ISSN
0007-0610

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Endemic Burkitt's lymphoma (eBL) is characterized by the presence of Epstein-Barr virus (EBV) and a chromosomal translocation which results in deregulation and constitutive expression of the c-myc proto-oncogene. In order to examine the role played by activation of c-myc in determining the eBL pheno