Derangements of immunoglobulin levels, phytohemagglutinin responsiveness and T and B cell markers in Down's syndrome at different ages

Precocious aging of the immune system in

Precocious aging of the immune system in Down syndrome: Alteration of b lymphocytes, T-lymphocyte subsets, and cells with natural killer markers

✍ Cossarizza, Andrea ;Monti, Daniela ;Montagnani, Giuliano ;Ortolani, Claudio ;Mas 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 679 KB

Phenotype and proliferative ability of peripheral blood lymphocytes from 15 noninstitutionalized children affected with Down Syndrome (DS), in apparently good health, were studied and compared with those of 16 healthy control children of the same age. A complex derangement of all the major periphera