Deracemization of 2-alkylcyclohexanones utilizing host-guest molecular association with optically active host compounds in basic suspension media

✍ Scribed by Tetsuto Tsunoda; Hiroto Kaku; Miwa Nagaku; Etsuko Okuyama

• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 159 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)10071-5

✦ Synopsis

Absfmct Based on host-guest inclusion complexation in the solid state, a-substituted cyclohexanones 2a-c were deracemized using optically active host compounds in alkaline conditions to optically active 2 in excellent chemical yield with high enantiometic excess. Q 1997 Elsevier Science Ltd.