✦ LIBER ✦
Der Stoffwechsel von Verbindungen mit Dreifachbindung. VII. Verteilung und Abbau der 9-Octadecinsäure bei Ratten, ein Beitrag zur α-Oxydation der C-Kette
✍ Scribed by Klaus Reichlmeier; Peter Graf; Ekkehard Kaempf; Karl Bernhard
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- German
- Weight
- 278 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Distribution and Metabolism of Octadec‐9‐ynoic acid in Rats
Octadec‐9‐ynoic acid (stearolic acid) fed to rats leads to the metabolic excretion of six dicarboxylic acids with retained triple bond. The main metabolic steps are ω‐, β‐, and presumably α‐oxidation. Feeding of ^14^C‐stearolic acid proves that the α‐oxidative steps involves the methyl end of the original acid. It could further be shown that this acid is incorporated partially in the body lipids. To a substantial degree it is totally oxidized and expired as ^14^CCO~2~.